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Christina Applegate makes heartbreaking SAG Awards announcement amid MS battle

Applegate is nominated for outstanding performance by a female actor in a comedy series for her role as Jen Harding in 'Dead to Me'
UPDATED FEB 8, 2023
Christina Applegate poses with her star during her Hollywood Walk of Fame Ceremony at Hollywood Walk Of Fame in Los Angeles (Phillip Faraone/Getty Images)
Christina Applegate poses with her star during her Hollywood Walk of Fame Ceremony at Hollywood Walk Of Fame in Los Angeles (Phillip Faraone/Getty Images)

ANAHEIM, CALIFORNIA: Christina Applegate is looking forward to the upcoming Screen Actors Guild Awards with mixed feelings. The 'Dead to Me' actress, who was diagnosed with multiple sclerosis in 2021, may have already made her final appearance when she said the next SAG Awards will likely be her last due to the effects of the disease.

Applegate is nominated for a Screen Actors Guild Award for her work in 'Dead To Me.' In a recent interview published Tuesday, February 7, that star said that "it's my last awards show as an actor probably, so it's kind of a big deal."

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What did Christina Applegate say?

Applegate recently talked about how challenging it would be for her to film another TV show at this point in her life. "Right now, I couldn't imagine getting up at 5.am and spending 12 to 14 hours on a set," Applegate said during her interview. "I don't have that in me at this moment."

Applegate admitted to the Los Angeles Times that she was unable to enjoy the final season of the series, although her performance in the show earned her a Critics Choice Award and a Screen Actors Guild Award nomination this year.

"I don't like seeing myself struggling. I gained 40 pounds because of inactivity and medications, and I didn't look like myself, and I didn't feel like myself," she said. "At some point I was able to distance myself from my own ego and realize what a beautiful piece of television it was. All the scenes I wasn't in were so much fun to see and experience for the very first time," as reported by Fox News.

The actress praised the "incredible" crew, the series' showrunner, and her co-stars, saying they were "Jen and Judy combined into a human, in the most perfect and beautiful way possible" — a reference to her character's friendship with Linda Cardellini, who plays Judy Hale. "I was a wreck every day," confessed Applegate, "but most of that wreck would take place in my trailer by myself. But there were times I'd break down on set and be like, 'I can't, we have to take a break, I need a half-hour,' and everyone was so loving that it was OK."

As reported by E! News Applegate noted, filming Dead to Me's last episodes was a reversal of what was happening in real life between her and Cardellini. "She literally pulled me under her wing and protected me, and took care of me every single day," Applegate said. "The tables were turned. Jen is taking care of her friend who's dying, yet Linda was taking care of me as I was saying goodbye to the person that I'd always known—so part of me was dying," she added. 

Christina Applegate attends the 28th Annual Critics Choice Awards at Fairmont Century Plaza on January 15, 2023 in Los Angeles, California.
Christina Applegate says SAG Awards will likely be her last award show as an actor (Matt Winkelmeyer/Getty Images)

Applegate discusses multiple sclerosis

Applegate has spoken openly about how difficult it was for her to film the final season of the popular Netflix series after learning of her diagnosis during filming. "Shooting the show was the hardest thing I've ever done in my life because I was diagnosed during shooting, and I didn't know it was happening to me," Applegate said in December 2022 on 'The Kelly Clarkson Show' "I couldn't walk. They had to use a wheelchair to get me to set. I was freaking out until someone was like, ‘You need an MRI.’" 

Applegate recalls having to call everyone she worked with to inform them of her diagnosis and to express her gratitude for their support during her illness. "If I called them in the morning and was like, ‘Guys, I can’t get down the stairs,’ they were like, ‘OK! We won’t do today. We’ll do other stuff.’ Netflix even let us take a break for a couple of months so that I could mourn and find treatment," Applegate told Variety in November 2022.

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