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What are Buprenorphine and Quetiapine? Medical examiner reveals cocktail of drugs found in Lisa Marie Presley’s system when she died

Lisa Marie Presley died at 54 years of age due to medical complications that arose from a weight-loss surgery she had years ago
PUBLISHED JUL 14, 2023
The singer died from sequelae of small intestinal blockage according to an LA County Medical Examiner's report (Joe Scarnici/Getty Images)
The singer died from sequelae of small intestinal blockage according to an LA County Medical Examiner's report (Joe Scarnici/Getty Images)

LOS ANGELES, CALIFORNIA: Lisa Marie Presley, 54, died in January from a tiny intestinal blockage brought on by prior weight-loss surgery; at the time of her death, opioids were discovered in her blood. The singer died from sequelae (a condition that is the result of a prior sickness or injury) of small intestinal blockage, according to an LA County Medical Examiner's report, after being brought to the hospital on January 12 after experiencing cardiac arrest.

Small bowel strangulation was the intestinal blockage, which was brought on by adhesions after years-old bariatric surgery (stomach stapling). Lisa had "therapeutic" amounts of Oxycodone in her blood, according to the toxicology reports, and a second drug, Buprenorphine, which is used to treat opioid dependency, was also discovered. Antipsychotic medication Quetiapine was also found, according to TMZ. The urine toxicology screen was negative, and the coroner reported that no "drug paraphernalia or narcotics" were discovered at her residence. Let's find out more about these drugs.

What are Buprenorphine and Quetiapine?

Lisa Marie Presley attends the premiere of Warner Bros. Pictures'
Lisa Marie Presley attends the premiere of Warner Bros Pictures' 'Mad Max: Fury Road' at TCL Chinese Theatre on May 7, 2015, in Hollywood, California (Kevin Winter/Getty Images)

Buprenorphine and Quetiapine are drugs that, when taken together, can increase the risk of an irregular heart rhythm and may be serious and potentially life-threatening. However, it is a rare side effect. A psychiatric medication, Quetiapine is used to treat bipolar disorder, schizophrenia, and major depressive disorder. Quetiapine is a second-generation atypical antipsychotic for treating these disorders. It was first licensed by the FDA in 1997.

The second drug, called Buprenorphine is used to treat opioid addiction. One of the three drugs frequently used to treat opioid addiction is Buprenorphine. Methadone and naltrexone are the other two, as reported by Daily Mail.

According to the source, Lisa underwent cosmetic treatment a few months before she died and was given an opioid prescription. The actress had a history of "overmedicating," which is the practice of forgetting to take medication and then taking it again.

The celebrity had a 'history of alcohol and drug abuse'

Musician Lisa Marie Presley poses at the Wonderwall portrait studio during the 2013 CMT Music Awards at Bridgestone Arena on June 5, 2013 in Nashville, Tennessee.
Musician Lisa Marie Presley poses at the Wonderwall portrait studio during the 2013 CMT Music Awards at Bridgestone Arena on June 5, 2013, in Nashville, Tennessee (Christopher Polk/Getty Images)

According to reports, the celebrity had a history of alcohol and drug abuse. Two days before her death, Lisa Marie, a singer-songwriter who released three studio albums between 2003 and 2012, had just returned from the 80th Golden Globe Awards in Los Angeles with her mother, Priscilla.

The mother-daughter team made a point to attend the ceremony in favor of Baz Luhrmann's critically praised biopic Elvis, which starred Austin Butler as the famous King of Rock and Roll, Elvis Presley. Lisa Marie leaned on her 81-year-old family friend Jerry Schilling as she walked the red carpet for the event and she seemed feeble and vulnerable.

According to sources who spoke to TMZ, Lisa Marie's housekeeper discovered her unconscious in her bedroom, and she had been residing with her ex-husband Danny Keough, who gave her CPR until paramedics came. According to the source, "epinephrine," often known as adrenaline was "administered" at least once at the site to help Lisa Marie restore a pulse. Stomach discomfort is a sign of female cardiac arrest, according to the Mayo Clinic.

Adrenaline, also known as epinephrine, is given to patients to treat various life-threatening health problems, such as cardiac arrests, asthma attacks, and allergic responses. According to The Hollywood Reporter, she was taken to West Hills Hospital when the fire crew attended and was able to take her pulse.

Lisa Marie was attempting to slim down

Lisa Marie Presley attends the Handprint Ceremony honoring Priscilla Presley, Lisa Marie Presley And Riley Keough at TCL Chinese Theatre on June 21, 2022 in Hollywood, California.
Lisa Marie Presley attends the Handprint Ceremony honoring Priscilla Presley at TCL Chinese Theatre on June 21, 2022, in Hollywood, California (Jon Kopaloff/Getty Images)

For the Elvis Awards season, Lisa Marie was attempting to slim down, and in the weeks preceding her death, she had even started using opiods. Before the Golden Globe Awards, the celebrity got plastic surgery and followed a stringent diet plan to lose up to 50 pounds, as per reports.

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