'Best Medicine' filming location revealed as Fox comedy lands special advance premiere

Fox's new series, adapted from the British show 'Doc Martin', debuted on Sunday, January 4
PUBLISHED JAN 5, 2026
A screenshot of Josh Charles from 'Best Medicine' (Cover Image Source: YouTube | @tvpromo360)
A screenshot of Josh Charles from 'Best Medicine' (Cover Image Source: YouTube | @tvpromo360)

Fox is all set to entertain its viewers with an official remake of the British series 'Doc Martin', titled 'Best Medicine.' The trailer of the comedy series offers a glimpse into the world of the show, with Dr. Martin Best (Josh Charles) taking center stage. The 'Best Medicine' trailer also reveals that the series is set in the charming East Coast fishing village of Port Wenn, leaving many fans wondering if the town actually exists in real life.

Screenshot of Josh Charles from 'Best Medicine' (Cover I age Source: YouTube |@tvpromo360)
A screenshot of Josh Charles from 'Best Medicine' (Image Source: YouTube |@tvpromo360)

Although Best Medicine is set in the small town of Port Wenn, Maine, the town is fictional, and the series was actually filmed in Cornwall, New York. During a set visit with Us Weekly, Abigail Spencer, who plays a central character on the show, commented on the change of scenery, saying, "It's nice. I've actually done quite a few shows where we lived in a house with my producer and my costars. When I did Rectify, we were in Georgia. It just feels more like you're going there to make something altogether." She added, "And then you're really invested in the community. I've made friends a lot with the local businesses. That's part of what we get to do is invest in community as well."

Notably, 'Best Medicine' follows a doctor who, according to the official synopsis, "moves from the city of Boston, Massachusetts, to a small practice in the East Coast fishing village where he vacationed as a child." The series centers on his adjustment from city life to the quirks and challenges of practicing medicine in a close-knit small-town community. The show had a special advance premiere on Sunday, January 4, 2026, on FOX. It will air in its regular time slot on Tuesdays at 8 pm ET/PT.

The series opener, titled 'Docked', will re-air on Tuesday, January 6, at 8 pm, followed by the winter premiere of medical drama 'Doc', as per Deadline. Producer Ben Silverman shared in a Fox press release that the British show 'Doc Martin' "first came to me through my mother and then, separately, through my father. They're divorced but both artists with exceptional taste," as per Parade.

He added, "I immediately fell in love with Doc Martin, just as I did with the original versions of The Office and Ugly Betty. I know that there had been talks for years about when Doc Martin would come to the U.S., and we knew we needed to take our time to get this right. It is truly rare to find underlying material that so naturally and powerfully translates for an American audience at this specific moment."

GET THE BIGGEST ENTERTAINMENT STORIES
STRAIGHT TO YOUR INBOX.

MORE STORIES

A new supe is now in possession of the V1 compound, and the character is yet to make an appearance in 'The Boys' Season 5.
1 hour ago
The introduction of the new and young character in ‘Daredevil: Born Again’ Season 2 Episode 6 also connects to the future MCU.
7 hours ago
Episode 7, titled 'The Hateful Darkness,' of 'Daredevil: Born Again' Season 2 is set to break a sad record.
9 hours ago
Jamie Ding edges closer to a historic ‘Jeopardy’ streak after a tense final round
10 hours ago
The latest episode saw Jessica Jones join Matt Murdock's efforts to end the Kingpin's reign over New York City
10 hours ago
As the hit Prime Video series reaches the midway mark, the latest rumored leaks tease an absolute bloodbath.
11 hours ago
‘Unchosen’ revolves around Adam (Asa Butterfield) and his wife Rosie (Molly Windsor) as they navigate life in a strict religious community
11 hours ago
In a video on social media, Sonja Sohn claims that there is much more to her exit from 'Will Trent' than people know.
11 hours ago
A desperate escape and a haunting chase lead to a final twist, as ‘Unchosen’ ends with one character in control while others struggle to break free.
12 hours ago
LL Cool J returns as Special Agent Sam Hanna and helps the NCIS team with their latest case
12 hours ago