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'Supergirl' Season 5 will see Kara Danvers face-off against ancient Atlanteans Rama Khan and Gamemnae

The pair were first seen in the 2002 comic JLA as ancient Atlanteans. At this stage, we don't know if the episode in the series has any connection to Aquaman or will have fleeting references

Cara Buono's Gamemnae may be more than Kara Danvers' foe in the upcoming season of 'Supergirl'. When it was announced that 'Stranger Things' star Cara Buono would be playing Gamemnae, fans instantly connected to the Atlantean exiled to the surface at birth for being born with blond hair.

She survives the exile while honing her sorcery skills. In the series though, she is part of an alien race, who "have been safeguarding the Earth from the follies of humanity throughout the ages."

According to Deadline, Gamemnae's aim is to use technology to subjugate humans. She is cunning, witty, ruthless, and always 10 steps ahead of her adversaries.

Gamemnae's agenda puts her into conflict with her would-be allies and on a collision course with Supergirl. While it is unclear if the duo will eventually forge an alliance, it is clear that the network has already started factoring in Atlantis as one of its key plot points. 

Joining her will be Mitch Pileggi  ('X-Files') as Rama Khan, one of the ancient rulers of Atlantis. He has the power to control all four elements (fire, water, earth, and air) to protect the Earth from humankind.

The pair were first seen in the 2002 comic JLA as ancient Atlanteans. While the storyline of 'Supergirl' may give their introductions a twist, the Atlantis part is a surprise saved for the fans.

At this stage, we don't know if the episode in the series has any connection to Aquaman or maybe fleeting references.

For all we know, there might be no Aquaman connect either, but it's a great prospect to look forward to as the series is slowly going ahead and expanding the DC Universe by introducing characters not seen before.

Rama Khan and Gamemnae may be Kara's foes, but that's not all she's got on her plate in the new season. With Lena Luthor (Katie McGrath) finding out that Kara is Supergirl, the feeling of betrayal has crept in and she'll be looking to settle the score.

And, there's the 'Crisis' to prepare for. Things certainly look grim for the Girl of Steel. 'Supergirl' season 5 debuts on October 6 on The CW.