Netflix 'Oxygen' Full Cast List: Meet Melanie Laurent, Mathieu Amalric and rest of the stars of sci-fi thriller movie

The film is carried almost solely on actor Melanie Laurent's shouders as she plays scientist Elizabeth Hansen
'Oxygen' stars Melanie Laurent (Netflix)
'Oxygen' stars Melanie Laurent (Netflix)

Feeling hemmed in is unfortunately a feeling the world is rather familiar with right now. But 'Oxygen' takes feeling claustrophobic to a whole new level. The sci-fi film, which was shot within the confines of strict safety protocols during the pandemic, focuses on what occurs when a scientist wakes up to find herself trapped in cryogenic pod, with no idea how she got there or who she is. Since she is running out of oxygen, she has to rebuild her memory to find her way out. Let's now meet the cast of the film. 

RELATED ARTICLES

Josh Brolin poses naked with Hawaiian wahoo fish to highlight plight of marine life

'Sound of Metal': Meet Riz Ahmed, Olivia Cooke, Lauren Ridloff and rest of the cast of Amazon Prime's drama film

'Oxygen' stars Melanie Laurent (Netflix)

Melanie Laurent as Elizabeth Hansen

Melanie Laurent plays scientist Elizabeth Hansen, who wakes up to find herself in a cryogenic pod with no idea of who she is. Laurent carries the film almost solely on her shoulders, which is not surprising considering the body of work the actor has built over the years. Laurent of course made her Hollywood debut with Quentin Tarantino's colossal hit 'Inglourious Basterds'. However, Melanie Laurent was already an extremely highly regarded actor in France. Laurent was discovered by French acting legend Gérard Depardieu who gave her a minor role in the romantic drama, 'The Bridge'. But it was enough to pave the way for an extremely successful acting career. Laurent who is the recipient of two César Awards and a Lumières Award, has worked mainly in independent films, including 'Paris' and 'Enemy' but has also appeared in commercial Hollywood films, including 'Now You See Me'.

Melanie Laurent stars in 'Oxygen' (Getty Images)

Mathieu Amalric as M.I.L.O

Mathieu Amalric voice permeates 'Oxygen' as M.I.L.O, which stands for (Medical Interface Liaison Operator), a helpful talking computer that is Laurent's only source of help and hope. Amalric has been part of several Hollywood blockbusters such as 'Quantum of Solace' and has also been a part of critically appreciated films such as 'The Grand Budapest Hotel' and more recently the Oscar-nominated 'Sound of Metal'. 

Mathieu Amalric stars in 'Oxygen' (Getty Images)

Malik Zidi as Leo Ferguson 

Malik Zidi is a French film, television and theater actor who is the recipient of the Cesar award for Most Promising Actor. He is best known for his roles in films such as 'Changing Times' in which he starred with Catherine Deneuve and 'Poison Friends', which was showcased at the Cannes Film Festival and received the Critics Week Grand Prize.

Malik Zidi stars in 'Oxygen' (Getty Images)

Marc Saez as Ortiz

Marc Saez is an actor and writer who is best known for his roles in projects such as 'Borgia' 'Day of Atonement' and 'Suivez la flèche'.

Other stars

'Oxygen' also stars Laura Boujenah, Lyah Valade and Cathy Cerda.

Creators

'Oxygen' is directed by Alexandre Aja and written by Christie LeBlanc.

You can catch the trailer of the film which will debut on Netflix on May 12 below:



 

GET THE BIGGEST ENTERTAINMENT STORIES
STRAIGHT TO YOUR INBOX.

MORE STORIES

‘A Dog’s Perfect Christmas’ captures Michigan’s Christmas vibes in another country
2026-11-10T11:25:54.000Z
One decision from Hunter and a surprise in the closing moments wrap up the Goss family story
2026-11-10T10:17:31.000Z
James Gunn is stepping down as DC Studios co-CEO but has another project in development for the franchise, raising questions about his future as a director
2026-11-10T09:23:55.000Z
Cole Hauser’s next project follows FBI undercover agent Scott Payne’s two decades of dangerous missions, including infiltrating a neo-Nazi group.
2026-11-10T06:13:30.000Z
The film adapts a memoir about a grieving New York writer and the famed neurologist he fell in love with
2026-11-10T04:01:27.000Z
Pattinson and Washington lead Netflix’s 'The Take,' a heist thriller about a bank robbery filled with deception and double crosses.
2026-11-09T20:31:44.000Z
Suburbia meets dinosaur territory in Anne Hathaway and Ewan McGregor’s ‘The End of Oak Street,’ arriving soon on HBO Max.
2026-11-07T19:01:32.000Z
The search for Daniel Craig’s James Bond successor takes another turn as two familiar faces reportedly enter the race for 007.
2026-11-07T13:45:19.000Z
Paramount slots the Hasbro reimagining just ahead of Halloween, with McBride directing his first feature
2026-11-07T10:09:36.000Z
‘Heated Rivalry’ will be showcased in a special event from November 6 to November 30
2026-11-07T08:42:14.000Z